683 research outputs found

    Models of cellular radiation action

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    An algorithm for LET-analysis

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    An algorithm for the derivation of LET-distributions from pulse- height spectra obtained with proportional counters is described. The method is based on Fourier transformation: it is applicable to spherical as well as non-spherical proportional counters. The relation between the energy mean, LD, of LET and the energy mean, yD, of the lineal energy density is given

    Microdosimetry of diagnostic X-rays: applications of the variance-covariance method.

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    Microdosimetric measurements in beams of diagnostic X rays (between 30 and 125 kV) have been performed. In these pulsed radiation fields, microdosimetric measurements are possible only by application of the variance-covariance technique. The dose mean lineal energy, yD, is determined for various simulated diameters, at different depths in the absorber, and at different points within the pulse intervals. From the measured temporal dependences one can also obtain values of yD for different X-ray pulse generators. The results demonstrate the potential of the variance-covariance method for a diversity of microdosimetric measurements in radiation protection and in the quality control of radiation beams

    Summary of the discussion on mammary carcinogenesis in the rat

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    Criteria of applicability for autoradiography of tritium

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    Autoradiography is an effective tool for the imaging of radionuclide distributions in various samples. In sophisticated applications with special preparation and development of sample-emulsion combinations and subsequent grain counts it can be highly quantitative, but it requires carefully controlled conditions and a variety of counter-checks, for example through scintillation spectroscopy. Less refined applications use X-ray films as detectors, and their seeming simplicity tends to invite artefacts and misinterpretations. Particular care needs to be taken, if one deals, or presumes to deal, with the low-energy ß-emitter tritium. Because of the short electron ranges the film must be in intimate contact with the sample, which tends to produce chemographic artefacts; without added spectroscopic measurements it is impossible to discriminate the spurious signals from a blackening of the film due to tritium. Recent statements concerning autoradiographic tritium measurements in tree samples have created considerable public concern and have demonstrated the pitfalls of uncritical use. This paper presents order-of-magnitude criteria for the detection threshold in the autoradiography of tritium; they can serve as an exclusion principle for some of the more extravagant misinterpretations. Dedication to Prof. Wolfgang Jacobi on the occasion of his 65th birthda
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